Schedule (continuous update)
13:30-14:00 Registration
14:00-14:10 Welcome address: James Yang(National Taiwan University Cancer Center, Taiwan)
Welcome address: Pai-Chi Li(National Taiwan University, Taiwan)
Plenary Session 1: Inventing Spatial Technology
Moderator: Ruby Yun-Ju Huang (National Taiwan University, Taiwan)
14:10-14:40 Jerry Jia-Ren Lin (Harvard Medical School, USA)
‘Multiplexed tissue imaging in translational research: from colorectal cancer to renal diseases’
14:40-15:10 Jung-Chi Liao (SYNCELL, Taiwan)
‘Microscopy-Guided Subcellular Protein Pulldown and Discovery of Novel Proteomes’
15:10-15:40 Shih-Yu Chen (Academia Sinica, Taiwan)
‘Decoding the Complexity of Cellular Heterogeneity with Multi-Omic Single-Cell Analysis’
15:40-15:50 Selected short talk
Kim Kira Witetzek (Academia Sinica, Taiwan)
‘ATAC-MASS Enables Holistic Chromatin Accessibility Analysis by Seqencing, MASS Cytometry, and High-Resolution Imaging’
15:50-16:20 Panel discussion 1: How have we got this far?
Speakers: Ruby Yun-Ju Huang (National Taiwan University, Taiwan)
Joseph Beechem (NanoString Technologies, USA)
Jung-Chi Liao (SYNCELL, Taiwan)
Paul Rasmussen (Vizgen, Singapore)
16:20-17:00 Poster display + light bites
First Day closes
FRIDAY, MAY 24
08:30-09:00 Registration
09:00-09:05 Open Day 2
Plenary Session 2 Spatial Technology in Tumor Heterogeneity
Moderator: Chiun Hsu (National Taiwan University Hospital, Taiwan)
09:05-09:35 Ramanuj Dasgupta (A*STAR, Singapore)
‘Interrogating tumor evolution “in time and space’
09:35-10:05 Muh-Hwa Yang (National Yang Ming Chiao Tung University, Taiwan)
‘Spatial evolution throughout the progression of head and neck
cancer’
10:05-10:35 Wei Dai (The University of Hong Kong, Hong Kong)
‘Spatial Multi-Omics Study to Identify Risk Factors for Distant Metastasis in Epstein-Barr Virus-associated Nasopharyngeal Carcinoma’
10:35-11:00 Break
Plenary Session 3: Breakthrough in Spatial Multi-Omics
Moderator: Hsueh-Fen Juan (National Taiwan University, Taiwan)
11:00-11:35 Joseph Beechem (NanoString Technologies, USA)
‘Spatial Single Cell Whole Transcriptome Imaging (19000-plex) in Tissue and Fixed-Cells using CosMx Spatial Molecular Imaging’
11:35-12:05 Arutha Kulasinghe (Wesley Research Institute, Australia)
‘Ultra-deep tumour microenvironment profiling to discover biomarkers associated with response and resistance to therapy’
12:05-12:35 Nikhil Rao (10x Genomics, USA)
‘Combine the power of single cell & spatial to make the impossible, possible. That’s Xenium potential’
12:35-13:30 Lunch + Poster display
Plenary Session 4: Spatial Thinking in Study Design
Moderator: Che Lin (National Taiwan University, Taiwan)
13:30-14:00 Somponnat Sampattavanich (Siriraj Hospital & Mahidol University, Thailand)
‘Advancing Precision Medicine for Rare Cancers via Spatial Biology’
14:00-14:30 Chia-Lang Hsu (National Taiwan University Hospital, Taiwan)
‘Spatial transcriptome insights into the aggressiveness stratification in pre-invasive lung cancer’
14:30-14:45 Ya-Ling Hsu (Kaohsiung Medical University, Taiwan)
‘The investigation of tumor microenvironment: from and pre-metastatic niche to metastatic niche by multi-omics technique’
14:45-15:15 Break
Plenary Session 5: Transforming Pathology with Spatial Technology
Moderator: Yung-Ming Jeng (National Taiwan University Hospital, Taiwan)
15:15-15:45 Joe Poh Sheng Yeong (A*STAR and Singapore General Hospital, Singapore)
‘Spatial-powered AI Pathology H&E 2.0: a New era’
15:45-16:15 Ruby Yun-Ju Huang (National Taiwan University, Taiwan)
‘Seeing the Signatures of Tumor Heterogeneity’
16:15-16:45 Paul Rasmussen (Vizgen, Singapore)
‘MERSCOPE® Platform Harnessing Unparalleled Flexibility and Class-Leading Sensitivity for High-Resolution Spatial Biology’
16:45-16:55 Selected short talk
Duncan Yi-Te Wang (National Taiwan University, Taiwan)
‘Spatially-Resolved Profiling of Advanced Ovarian Clear Cell Carcinoma Reveals Intra-Tumor Heterogeneity in Epithelial-Mesenchymal Gradient’
16:55-17:35 Poster display+ light bites
17:35- Speakers’ Dinner_ Ganbei Taipei Main Station (Location: 2, 3, Beiping West Road, Zhongzheng District, Taipei City, Taiwan)
Second day closes
SATURDAY, MAY 25
08:30-09:00 Registration
09:00-09:05 Open Day 3
Special Keynote 2
Moderator: Ruby Yun-Ju Huang (National Taiwan University, Taiwan)
09:05-10:00 Yu-Ju Chen (Academia Sinica, Taiwan)
‘Nanoscale-to-Single Cell Proteomics by Chip-DIA Mass
Spectrometry’
Plenary Session 6：Multi-Omics of the future
Moderator: Ruby Yun-Ju Huang (National Taiwan University, Taiwan)
10:00-10:30 Fiona Kaper (Illumina, USA)
‘Accelerating Discoveries in Spatial Biology through the Illumina Ecosystem’
Special Keynote 3
Moderator: Ruby Yun-Ju Huang (National Taiwan University, Taiwan)
10:30-11:20 Xiaowei Zhuang (Havard University, USA)
‘Spatially resolved single-cell genomics & cell atlas of the brain’
11:20-11:30 Selected short talk
Wye-Lup Kong (Academia Sinica, Taiwan)
‘Spatial transcriptome with MAS-IsoSeq: a-MAIZE-zing resolution for leaf embryogenesis’
11:30-11:40 Selected short talk
Ying-Xuan Li (National Taiwan University Hospital, Taiwan)
‘Inter- and intra-tumor heterogeneous immune presentation in primary uterine carcinosarcoma determined by digital spatial profiling expression’
11:40-12:10 Panel discussion 2: Where do we go from here?
Speakers: Ruby Yun-Ju Huang (National Taiwan University, Taiwan)
Arutha Kulasinghe (Wesley Research Institute, Australia)
Somponnat Sampattavanich (Siriraj Hospital & Mahidol
University, Thailand)
Ramanuj Dasgupta (A*STAR, Singapore)
12:10-12:15 Closing Remarks: Ruby Yun-Ju Huang
Social Event: Guided Tour of KAVALAN Whisky Distillery ( Voluntary participation )